Discover New Hair Loss Causes

Hair loss causes

In the search for hair loss causes and male pattern baldness, researchers from the Perelman School of Medicine at the University of Pennsylvania have identified a protein known as Prostaglandin D2, which would be the cause of hair loss and male pattern baldness.

Examining hair loss causes of men bald areas of male pattern baldness and comparing hair populated areas of non-balding men, researchers found the presence of abnormal amounts of protein Prostaglandin D2 and corroborated these findings in mouse models. Prostaglandin D2 levels were up to 3 times higher in men with male pattern baldness.

Hair loss causes and Prostaglandin D2

 When they added more amount of Prostaglandin D2 protein to hair follicles, these were reduced in size significantly. New causes of hair loss?

The researchers found that in both humans and animals, Prostaglandin D2 protein inhibited hair growth male pattern baldness, the most common cause for hair loss in men. This discovery could lead to the creation and implementation of new treatments for hair loss and eventually to the solution of a problem that affects hundreds of millions of men worldwide. As known male pattern baldness affects 8 in 10 men over 70 years.

The hair growth inhibition occurs through a receptor called GPR44 and answers are sought to overcome this deficiency biological. This information appeared in March of this year in ScienceDaily and originally the study was published in Science Translational Medicine

Hair loss Causes, Role of Prostaglandins

 It is well known the role of prostaglandins in many bodily functions, for example controlling the expansion of muscle tissue and cell growth and particularly prostaglandin F2 alpha, speed and stimulates hair growth

The dr. George Cotsarelis, a professor of dermatology, and lead author of the study, said that when looking at the hair follicle stem cells, found this unexpected discovery that had not been previously associated prostaglandins to hair loss, although it was known that certain prostaglandins , F2 alpha specifically stimulated hair growth.

The research team of Dr. Cotsarelis, was composed of the doctors Luis Garza, Yaping Liu, Yang Zaixin, Brinda Alagesan, Scott Norberg, Tailun Zhao, Hanz Blatt, David Stanton and Lee Carrasco
Hair Loss Causes-Studies

Additional studies are needed to certify the validity of these findings as new hair loss causes and to discover new treatments for hair loss through topical applications benefit men and women suffering from hair loss and baldness.

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